HPLC Column, IEX WCX, 5um, 4.6mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent IEX WCX is a weak cation exchange (WCX) HPLC stationary phase designed for the retention and separation of positively charged compounds. Manufactured using high-purity silica and carboxylic acid functional groups, the stationary phase provides a negatively charged surface within its functional pH range of approximately 2.5 to 7, enabling reliable cation exchange selectivity for basic compounds and other positively charged analytes. This popular chromatography phase has been widely used in HPLC laboratories for many years and serves as an excellent alternative for many USP L9 methods.
67591-15P is a 150 mm x 4.6 mm ID analytical HPLC column packed with 5 µm WCX particles with a 100 Å pore size. The 150 mm column length provides increased resolving power and peak capacity compared to shorter columns, making it ideal for impurity profiling, method optimization, and separation of closely related basic compounds. The 4.6 mm ID format is the industry standard for conventional HPLC systems and typically operates at approximately 1.0–2.0 mL/min, providing robust performance and excellent method transferability.
This weak cation exchange column is particularly useful for the analysis and purification of basic pharmaceuticals, amines, peptides, proteins, and other positively charged compounds. The combination of selective WCX functionality, high-purity silica, and efficient 5 µm particles delivers reproducible chromatography and dependable performance for challenging ion exchange applications requiring enhanced resolution and superior separation efficiency.
Key Benefits
Weak cation exchange (WCX) stationary phase
Carboxylic acid functional groups
Suitable for positively charged analytes
Alternative for many USP L9 methods
High-purity silica support
5 µm particles for efficient separations
Enhanced resolution from 150 mm column length
Increased peak capacity for complex samples
Reliable and reproducible ion exchange performance
Typical Applications
Ion exchange chromatography
Cation separations
Basic compound analysis
Pharmaceutical analysis
Amine separations
Peptide analysis
Protein analysis
USP L9 methods
Impurity profiling
Method development
Purification of positively charged compounds
Specifications
Product Type: HPLC Column
Stationary Phase: IEX WCX
USP Classification: L9
Chromatography Mode: Weak Cation Exchange
Functional Group: Carboxylic Acid
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 150 mm
Length: 150 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Brand: Cogent
Important Notes
Designed for weak cation exchange chromatography
Retains positively charged analytes
Functional charged range approximately pH 2.5–7
Suitable for many USP L9 applications
High-purity silica provides reliable chromatographic performance
Longer column length improves separation of closely related compounds
Compatible with conventional HPLC systems
Excellent choice for impurity profiling and method development